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Anti-SPI1 / PU.1 Antibody
Rabbit Anti Human Polyclonal Antibody
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Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P17947 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 31083 Da |
| Dilution | ELISA, IHC-P (10 µg/ml), WB |
| Gene ID | 6688 |
|---|---|
| Alias Symbol | SPI1 |
| Other Names | SPI1, 31 kDa-transforming protein, 31 kDa transforming protein, PU.1, SFPI1, SPI-1, SPI-1 proto-oncogene, SPI-A, Transcription factor PU.1 |
| Target/Specificity | Human SPI1 / PU.1 |
| Reconstitution & Storage | PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Anti-SPI1 / PU.1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SPI1 |
|---|---|
| Function | Binds to the PU-box, a purine-rich DNA sequence (5'- GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B- cells. Also binds RNA and may modulate pre-mRNA splicing (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00237, ECO:0000269|PubMed:23166356} |
Research Areas
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$ 425.00
Cat# ALS17274
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