|Application ||WB, IHC-P, E, IP, ID, Flo|
|Calculated MW||52602 Da|
|Dilution||ELISA, Flo, ID, IHC-P (5 µg/ml), IP, WB|
|Other Names||SERPINC1, Antithrombin III, Antithrombin-III, ATIII, AT3, Serpin C1, AT3D, THPH7|
|Target/Specificity||Human Antithrombin III|
|Reconstitution & Storage||10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2, 0.05% sodium azide. Store at 2-8°C|
|Precautions||Anti-Antithrombin-III Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.|
|Cellular Location||Secreted, extracellular space.|
|Tissue Location||Found in plasma.|
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