|Calculated MW||39295 Da|
|Dilution||IHC-P (5 - 10 µg/ml)|
|Other Names||HCAR1, FKSG80, G protein-coupled receptor 81, G-protein coupled receptor 104, G protein-coupled receptor 104, G-protein coupled receptor 81, GPR81, GPR104, LACR1, HCA1, TA-GPCR, Lactate receptor 1|
|Target/Specificity||Human GPR81. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||PBS, less than 0.1% sodium azide. Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.|
|Precautions||Anti-FKSG80 / GPR81 Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPR104, GPR81, HCA1|
|Function||Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed abundantly in brown and white fat. It also detectable at lower levels in liver, kidney, skeletal muscle, brain and pituitary. Not detected in frontal, temporal and occipital lobes of the cortex, basal forebrain, caudate nucleus, nucleus accumbens and hippocampus.|
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