Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   Anti-DMN / Desmuslin / Synemin Antibody (aa329-580, clone 2F4)    

Anti-DMN / Desmuslin / Synemin Antibody (aa329-580, clone 2F4)

Mouse Anti Human Monoclonal Antibody

  • IHC-P - Anti-DMN / Desmuslin / Synemin Antibody (aa329-580, clone 2F4)  ALS17324
    Human Colon, Submucosa: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • IHC-P - Anti-DMN / Desmuslin / Synemin Antibody (aa329-580, clone 2F4)  ALS17324
    Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15061
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 2F4
Calculated MW 172768 Da
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 23336
Alias Symbol SYNM
Other Names SYNM, Desmuslin, KIAA0353, SYN, Synemin beta, Synemin, DMN, Synemin alpha
Target/Specificity Human DMN / Desmuslin / Synemin
Reconstitution & Storage PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide Store at -20°C. Minimize freezing and thawing.
PrecautionsAnti-DMN / Desmuslin / Synemin Antibody (aa329-580, clone 2F4) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DMN, KIAA0353, SYN
Function Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
Cellular Location Cytoplasm, cytoskeleton. Cell junction, adherens junction. Note=There are at least two distinct SYNM subpopulations, one in which SYMN interacts with DES within the Z- lines, and another in which it interacts with both DTNA and DES at the costamere
Tissue Location Isoform 2 is strongly detected in adult heart, fetal skeletal muscles and fetal heart. Isoform 1 is weakly detected in fetal heart and also in fetal skeletal muscle. Isoform 1 and isoform 2 are detected in adult bladder (at protein level) The mRNA is predominantly expressed in heart and muscle with some expression in brain which may be due to tissue-specific isoforms
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 425.00
Cat# ALS17324
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions