|Application ||WB, IHC-P, E, IP, ID, Flo|
|Calculated MW||45205 Da|
|Dilution||ELISA, Flo, ID, IHC-P (5 µg/ml), IP, WB|
|Other Names||HP, Binding peptide, Haptoglobin alpha(1S)-beta, Haptoglobin, beta polypeptide, Haptoglobin, Haptoglobin alpha(2FS)-beta, Haptoglobin, alpha polypeptide, HP2ALPHA2, BP, Zonulin, HPA1S|
|Reconstitution & Storage||10 mM sodium phosphate, 0.15 M sodium chloride, pH 7.2, 0.05% sodium azide. Store at 2-8°C|
|Precautions||Anti-HP / Haptoglobin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.