|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Monkey|
|Calculated MW||55769 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||CYP2D6, CPD6, CYPIID6, Cytochrome P450 2D6, CYP2D, CYP2D8P2, Cytochrome p450 iid6, CYP2D7P2, CYP2DL1, Cytochrome P450-DB1, Debrisoquine 4-hydroxylase, p450C2D, p450-DB1, p450DB1, CYP2D7AP, CYP2D7BP|
|Target/Specificity||Recognizes endogenous levels of Cytochrome P450 2D6 protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-CYP2D6 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein|
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