|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||54555 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||DFNA5, ICERE-1, Deafness, autosomal dominant 5, ICERE1|
|Target/Specificity||Recognizes endogenous levels of DFNA5 protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-DFNA5 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53 (PubMed:16897187, PubMed:18223688).|
|Cellular Location||Gasdermin-E, N-terminal: Cell membrane|
|Tissue Location||Expressed in cochlea. Low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta|
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