|Calculated MW||96530 Da|
|Dilution||IHC-P (20 µg/ml)|
|Other Names||ADGRD1, G protein-coupled receptor 133, GPR133, PGR25|
|Target/Specificity||Human GPR133. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||PBS, less than 0.1% sodium azide. Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.|
|Precautions||Anti-ADGRD1 / GPR133 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor. Signals via G(s)-alpha family of G- proteins (PubMed:22025619, PubMed:22575658). Has protumorigenic function especially in glioblastoma (PubMed:27775701).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Up-regulated in CD133(+) cell population of glioblastoma.|
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