|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||111651 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||ASAP2, AMAP2, Centaurin, beta 3, DDEF2, CENTB3, PAP, KIAA0400, SHAG1, PAG3, PAP-alpha|
|Target/Specificity||Recognizes endogenous levels of DDEF2 protein.|
|Reconstitution & Storage||PBS, pH 7.3, 0.01% sodium azide, 30% glycerol. Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||Anti-ASAP2 / DDEF2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration.|
|Cellular Location||Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups|
|Tissue Location||Detected in heart, brain, placenta, kidney, monocytes and pancreas.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.