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Anti-COMMD4 Antibody

Rabbit Anti Human Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H0A8
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Dilution ELISA, IHC-P (20 µg/ml), WB
Additional Information
Alias Symbol COMMD4
Other Names COMMD4, COMM domain containing 4
Target/Specificity Human COMMD4
Reconstitution & Storage Caprylic acid and ammonium sulfate precipitation
PrecautionsAnti-COMMD4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B.
Cellular Location Cytoplasm. Nucleus
Tissue Location Ubiquitous.. EMBL; AY542160; AAS22242.1; -; mRNA EMBL; AL136872; CAB66806.1; -; mRNA EMBL; CR533452; CAG38483.1; -; mRNA EMBL; AK000459; BAA91178.1; -; mRNA EMBL; AK314740; BAG37281.1; -; mRNA EMBL; AC068338; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471136; EAW99263.1; -; Genomic_DNA EMBL; BC000837; AAH00837.2; -; mRNA EMBL; BC068998; AAH68998.1; -; mRNA CCDS; CCDS10277.1; -. [Q9H0A8-1] CCDS; CCDS66834.1; -. [Q9H0A8-2] CCDS; CCDS66835.1; -. [Q9H0A8-3] RefSeq; NP_001271306.1; NM_001284377.1. [Q9H0A8-2] RefSeq; NP_001271307.1; NM_001284378.1. [Q9H0A8-3] RefSeq; NP_060298.2; NM_017828.4. [Q9H0A8-1] UniGene; Hs.351327; - ProteinModelPortal; Q9H0A8; - BioGrid; 120279; 49 CORUM; Q9H0A8; - IntAct; Q9H0A8; 18 STRING; 9606.ENSP00000267935; - iPTMnet; Q9H0A8; - PhosphoSitePlus; Q9H0A8; - DMDM; 51316094; - EPD; Q9H0A8; - MaxQB; Q9H0A8; - PaxDb; Q9H0A8; - PeptideAtlas; Q9H0A8; - PRIDE; Q9H0A8; - ProteomicsDB; 80236; - ProteomicsDB; 80237; -. [Q9H0A8-2] DNASU; 54939; - Ensembl; ENST00000267935; ENSP00000267935; ENSG00000140365. [Q9H0A8-1] Ensembl; ENST00000338995; ENSP00000340867; ENSG00000140365. [Q9H0A8-2] Ensembl; ENST00000480484; ENSP00000433662; ENSG00000140365. [Q9H0A8-1] Ensembl; ENST00000567195; ENSP00000457693; ENSG00000140365. [Q9H0A8-3] GeneID; 54939; - KEGG; hsa:54939; - UCSC; uc002azy.5; human. [Q9H0A8-1] CTD; 54939; - EuPathDB; HostDB:ENSG00000140365.15; - GeneCards; COMMD4; - HGNC; HGNC:26027; COMMD4 HPA; HPA066957; - MIM; 616701; gene neXtProt; NX_Q9H0A8; - OpenTargets; ENSG00000140365; - PharmGKB; PA134993083; - eggNOG; ENOG410IEAM; Eukaryota eggNOG; ENOG4111EZM; LUCA GeneTree; ENSGT00390000015516; - HOGENOM; HOG000006594; - HOVERGEN; HBG051069; - InParanoid; Q9H0A8; - KO; K22560; - PhylomeDB; Q9H0A8; - TreeFam; TF317482; - Reactome; R-HSA-8951664; Neddylation ChiTaRS; COMMD4; human GeneWiki; COMMD4; - GenomeRNAi; 54939; - PRO; PR:Q9H0A8; - Proteomes; UP000005640; Chromosome 15 Bgee; ENSG00000140365; - CleanEx; HS_COMMD4; - ExpressionAtlas; Q9H0A8; baseline and differential Genevisible; Q9H0A8; HS GO; GO:0005737; C:cytoplasm; IDA:LIFEdb GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-KW GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW CDD; cd04752; Commd4; 1 InterPro; IPR017920; COMM InterPro; IPR037356; Commd4 Pfam; PF07258; COMM_domain; 1 PROSITE; PS51269; COMM; 1 1: Evidence at protein level; Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Reference proteome; Transcription; Transcription regulation; Ubl conjugation pathway CHAIN 1 199 COMM domain-containing protein 4 /FTId=PRO_0000077393 DOMAIN 130 199 COMM. {ECO:0000255|PROSITE- ProRule:PRU00602} VAR_SEQ 101 186 Missing (in isoform 3). /FTId=VSP_055664 VAR_SEQ 128 187 MNRLAGVGWRVDYTLSSSLLQSVEEPMVHLRLEVAAAPGTP AQPVAMSLSADKFQVLLAE -> K (in isoform 2) /FTId=VSP_011394 SEQUENCE 199 AA; 21764 MW; 7B7B85234E3FB59B CRC64; MRFRFCGDLD CPDWVLAEIS TLAKMSSVKL RLLCSQVLKE LLGQGIDYEK ILKLTADAKF ESGDVKATVA VLSFILSSAA KHSVDGESLS SELQQLGLPK EHAASLCRCY EEKQSPLQKH LRVCSLRMNR LAGVGWRVDY TLSSSLLQSV EEPMVHLRLE VAAAPGTPAQ PVAMSLSADK FQVLLAELKQ AQTLMSSLG
Research Areas
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$ 565.00
Cat# ALS17977
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