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Anti-BMP2 Antibody (aa226-275)
Rabbit Anti Human Polyclonal Antibody
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Application ![]()
| WB, IHC-P, E |
---|---|
Primary Accession | P12643 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 44702 Da |
Dilution | ELISA, IHC-P (1:50), WB |
Gene ID | 650 |
---|---|
Alias Symbol | BMP2 |
Other Names | BMP2, BDA2, BMP-2, BMP-2A, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A |
Target/Specificity | BMP-2 antibody detects endogenous levels of BMP-2. |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-BMP2 Antibody (aa226-275) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BMP2 |
---|---|
Synonyms | BMP2A |
Function | Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451). |
Cellular Location | Secreted. |
Tissue Location | Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine |
Research Areas
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$ 505.00
Cat# ALS18089
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