|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Pig, Bovine|
|Calculated MW||54387 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||MMP20, AI2A2, Enamel metalloproteinase, Enamelysin, Matrix metallopeptidase 20, MMP-20, Matrix metalloproteinase-20|
|Target/Specificity||Recognizes endogenous levels of MMP20 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-MMP20 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Expressed specifically in the enamel organ.|
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