|Application ||WB, IHC-P, Flo|
|Calculated MW||34735 Da|
|Dilution||Flo (1:100), IHC-P (10 µg/ml), WB (1:1000 - 1:2000)|
|Other Names||ARG1, Arginase, liver, Arginase 1, Liver-type arginase, Liver arginase, Arginase-1, Type I arginase|
|Target/Specificity||Human ARG1 / Arginase 1|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-ARG1 / Arginase 1 Antibody (clone 4E6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.|
|Cellular Location||Cytoplasm. Cytoplasmic granule. Note=Localized in azurophil granules of neutrophils (PubMed:15546957)|
|Tissue Location||Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.