|Application ||WB, IHC-P|
|Calculated MW||29089 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:2000)|
|Other Names||FCGR3A, CD16A, CD16a antigen, CD16, FcgammaRIIIA, FCR-10, FCRIII, Fc gamma receptor III-A, Fc-gamma RIII, Fc-gamma RIII-alpha, FCG3, IGFR3, Fc- gamma riii, Fc-gamma receptor IIIb (CD16), Fc-gamma RIIIa, FCGR3, FCRIIIA, Neutrophil-specific antigen NA, ...|
|Target/Specificity||Human FCGR3A / CD16A|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-FCGR3A / CD16A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD16A, FCG3, FCGR3, IGFR3|
|Function||Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Secreted. Note=Exists also as a soluble receptor|
|Tissue Location||Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts|
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