|Application ||WB, IHC-P, IF, E|
|Calculated MW||35914 Da|
|Dilution||ELISA, IF, IHC-P (1:50), WB|
|Other Names||ACOT8, Acyl-CoA thioesterase 8, Acyl-coenzyme A thioesterase 8, ACTEIII, HNAACTE, HACTE-III, HACTEIII, PTE-1, Thioesterase II, Palmitoyl-CoA hydrolase, PTE1, Choloyl-CoA hydrolase, HTE, PTE-2, PTE2, Thioesterase III|
|Target/Specificity||ACOT8 Antibody detects endogenous levels of total ACOT8 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-ACOT8 Antibody (aa131-180) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ACTEIII, PTE1, PTE2|
|Function||Acyl-coenzyme A (acyl-CoA) thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:9299485, PubMed:9153233, PubMed:15194431). Competes with bile acid CoA:amino acid N-acyltransferase (BAAT) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (C2 to C20) (PubMed:9299485, PubMed:9153233). Inactive towards substrates with more than C20 aliphatic chains (PubMed:9153233). Involved in the metabolic regulation of peroxisome proliferation (PubMed:15194431).|
|Cellular Location||Cytoplasm. Peroxisome matrix. Note=Predominantly localized in the peroxisome (PubMed:10092594, PubMed:15194431)|
|Tissue Location||Detected in a T-cell line (at protein level). Ubiquitous (PubMed:9153233, PubMed:9299485)|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.