|Application ||WB, IHC-P, E|
|Calculated MW||63173 Da|
|Dilution||ELISA, IHC-P (1:50), WB|
|Other Names||C9, Complement C9, Complement component 9, Complement component C9|
|Target/Specificity||C9 Antibody detects endogenous levels of total C9 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-Complement C9 Antibody (aa181-230) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (PubMed:9634479, PubMed:9212048, PubMed:26841934). C9 is the pore- forming subunit of the MAC (PubMed:4055801, PubMed:26841934).|
|Cellular Location||Secreted. Target cell membrane; Multi- pass membrane protein. Note=Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore.|
|Tissue Location||Plasma (at protein level).|
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