|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||206942 Da|
|Dilution||IHC-P (5 µg/ml), WB (1:500 - 1:2000)|
|Other Names||PCSK5, HPC6, PC5, PC6A, Prohormone convertase 5, Protease PC6, Proprotein convertase 5, Proprotein convertase 6, SPC6, Subtilisin/kexin type 5, PC6|
|Target/Specificity||Human PC5 / PCSK5|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-PC5 / PCSK5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive and regulated secretory pathways. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha-integrins.|
|Cellular Location||Isoform PC6A: Secreted. Note=Secreted through the regulated secretory pathway.|
|Tissue Location||Expressed in T-lymphocytes.|
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