|Application ||WB, IHC, IHC-P|
|Calculated MW||19979 Da|
|Dilution||IHC, IHC-P (10 µg/ml), WB|
|Other Names||AGR2, AG2, AG-2, HPC8, HAG-2, Secreted cement gland homolog, Anterior gradient homolog 2, GOB-4, PDIA17, XAG-2|
|Reconstitution & Storage||Purified|
|Precautions||Anti-AGR2 Antibody (aa40-110, clone ABM22E6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion (PubMed:23274113).|
|Cellular Location||Secreted. Endoplasmic reticulum|
|Tissue Location||Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.|
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