|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat|
|Calculated MW||212455 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||PLXNA4, KIAA1550, PLXNA4A, Plexin A4, A, Plexin-A4, PLXNA4B, Plexin A4, Plexin A4, B, FAYV2820, PLEXA4, PRO34003|
|Target/Specificity||Recognizes endogenous levels of Plexin A4 protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-PLXNA4 / Plexin A4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1550, PLXNA4A, PLXNA4B|
|Function||Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.