|Application ||WB, IHC-P|
|Predicted||Human, Mouse, Rat, Monkey|
|Calculated MW||14700 Da|
|Dilution||IHC-P (1:100), WB (1:500 - 1:1000)|
|Other Names||FSHB, FSH Beta, Follitropin beta chain, Follitropin subunit beta, FSH-beta, Follitropin, beta chain, FSH-B|
|Target/Specificity||Recognizes endogenous levels of FSH beta protein.|
|Reconstitution & Storage||Immunoaffinity purified|
|Precautions||Anti-FSHB / FSH Beta Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (PubMed:2494176, PubMed:24692546). Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:407105, PubMed:8220432).|
|Cellular Location||Secreted. Note=Efficient secretion requires dimerization with CGA|
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