|Application ||WB, IHC-P|
|Calculated MW||48551 Da|
|Dilution||IHC-P (1:100), WB|
|Other Names||CCNA2, Cyclin-A2, Cyclin A2, CCN1, CCNA, Cyclin-A, G2/mitotic-specific cyclin a|
|Target/Specificity||Human CCNA2 / Cyclin A2.|
|Reconstitution & Storage||Affinity purified|
|Precautions||Anti-CCNA2 / Cyclin A2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.|
|Cellular Location||Nucleus. Cytoplasm Note=Exclusively nuclear during interphase (PubMed:1312467) Detected in the nucleus and the cytoplasm at prophase (PubMed:1312467). Cytoplasmic when associated with SCAPER (PubMed:17698606).|
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