Purified Mouse Monoclonal Antibody (Mab)
|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||29804 Da|
|Antigen Region||1-205 aa|
|Other Names||Prohibitin, PHB|
|Target/Specificity||This antibody is generated from a mice immunized with a recombinant protein between 1-205 amino acids from human.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PHB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.|
|Cellular Location||Mitochondrion inner membrane.|
|Tissue Location||Widely expressed in different tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
Sato T.,et al.Cancer Res. 52:1643-1646(1992).
Sato T.,et al.Genomics 17:762-764(1993).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (MAR-2005) to UniProtKB.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
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