Purified Mouse Monoclonal Antibody (Mab)
|Application ||WB, E|
|Calculated MW||25809 Da|
|Other Names||CD81 antigen, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, Tetraspanin-28, Tspan-28, CD81, CD81, TAPA1, TSPAN28|
|Target/Specificity||This CD81 antibody is generated from a mouse immunized with a recombinant protein between 113-204 amino acids from the human CD81.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CD81 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.|
|Cellular Location||Basolateral cell membrane; Multi-pass membrane protein. Note=Associates with CLDN1 and the CLDN1-CD81 complex localizes to the basolateral cell membrane|
|Tissue Location||Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines|
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Provided below are standard protocols that you may find useful for product applications.
May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV.
Oren R.,et al.Mol. Cell. Biol. 10:4007-4015(1990).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Livingston R.J.,et al.Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
Takahashi S.,et al.J. Immunol. 145:2207-2213(1990).
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