Purified Mouse Monoclonal Antibody (Mab)
|Application ||WB, E|
|Calculated MW||48804 Da|
|Other Names||Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39|
|Target/Specificity||This MYC antibody is generated from a mouse immunized with a recombinant protein of human MYC Isform 2.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MYC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000).|
|Cellular Location||Nucleus, nucleoplasm. Nucleus, nucleolus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Battey J.,et al.Cell 34:779-787(1983).
Bernard O.,et al.EMBO J. 2:2375-2383(1983).
Colby W.W.,et al.Nature 301:722-725(1983).
Watt R.,et al.Nature 303:725-728(1983).
Rabbitts T.H.,et al.Nature 306:760-765(1983).
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