Purified Mouse Monoclonal Antibody (Mab)
|Application ||WB, E|
|Calculated MW||133470 Da|
|Other Names||Integrin alpha-11, ITGA11|
|Target/Specificity||This ITGA11 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 675-880 amino acids from human ITGA11.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ITGA11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Integrin alpha-11/beta-1 is a receptor for collagen.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Integrin alpha-11/beta-1 is a receptor for collagen.
Lehnert K.,et al.Genomics 60:179-187(1999).
Velling T.,et al.J. Biol. Chem. 274:25735-25742(1999).
Zody M.C.,et al.Nature 440:671-675(2006).
Xu Y.Y.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Pellinen T.,et al.J. Cell Biol. 173:767-780(2006).
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