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REG1A Antibody

Purified Mouse Monoclonal Antibody

  • IHC - REG1A Antibody AO1293a
    Figure 1: Immunohistochemical analysis of paraffin-embedded human Pancreas tissues using REG1A mouse mAb
  • IF - REG1A Antibody AO1293a
    Figure 2: Confocal immunofluorescence analysis of PC12 cells using REG1A mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
  • WB - REG1A Antibody AO1293a
    Figure 1: Western blot analysis using CK17 mouse mAb against Hela (1), MCF-7 (2) and A431 (3) cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05451
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1A4
Isotype IgG1
Calculated MW 19kDa
Description REG1A (regenerating islet-derived 1 alpha), also known as PTP, PSP, is a member of the Reg family of secreted proteins with a C-type lectin domain. REG1A is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis.Due to variable glycosylation, pancreatic REG1A exists as multiple species of 16 - 18 kDa. REG1A promotes the maintenance and growth of pancreatic islet β-cells and intestinal villi. It is upregulated in pancreatitis and some carcinomas. REG1A is an antigenic target in autoimmune diabetes.
Immunogen Purified recombinant fragment of human REG1A fused with hIgGFc tag expressed in HEK293 cell line.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 5967
Other Names Lithostathine-1-alpha, Islet cells regeneration factor, ICRF, Islet of Langerhans regenerating protein, REG, Pancreatic stone protein, PSP, Pancreatic thread protein, PTP, Regenerating islet-derived protein 1-alpha, REG-1-alpha, Regenerating protein I alpha, REG1A, PSPS, PSPS1, REG
Dilution IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsREG1A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name REG1A
Synonyms PSPS, PSPS1, REG
Function Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
Cellular Location Secreted.
Tissue Location In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients
Research Areas
Citations (0)

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1. Pancreas. 2004 Jul;29(1):14-21. 2. Int J Cancer. 2008 Jul 15;123(2):409-13.

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$ 325.00
Cat# AO1293a
Availability: 7-10 days
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