|Application ||WB, IHC, FC, ICC, E|
|Description||Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.Tissue specificity: Mammary gland specific. Over-expressed in breast cancer.|
|Immunogen||Purified recombinant fragment of human SCGB2A2 expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Other Names||Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2, SCGB2A2, MGB1, UGB2|
|Dilution||WB~~1/500 - 1/2000|
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SCGB2A2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Mammary gland specific. Over-expressed in breast cancer|
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Provided below are standard protocols that you may find useful for product applications.
1. Ann Oncol. 2006 Jun;17 Suppl 7:vii41-5. 2. Mod Pathol. 2007 Feb;20(2):208-14.
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