|Application ||WB, IHC, ICC, E|
|Description||This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development.Tissue specificity: Expressed in brain.|
|Immunogen||Purified recombinant fragment of human OTX2 expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide.|
|Other Names||Homeobox protein OTX2, Orthodenticle homolog 2, OTX2|
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OTX2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor probably involved in the development of the brain and the sense organs. Can bind to the bicoid/BCD target sequence (BTS): 5'-TCTAATCCC-3'.|
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1. Hum Mutat. 2008 Nov;29(11):E278-83. 2. Cancer Res. 2010 Jan 1;70(1):181-91.
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