|Application ||WB, IHC, FC, E|
|Description||The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli.|
|Immunogen||Purified recombinant fragment of human CRP expressed in E. Coli. |
|Formulation||Ascitic fluid containing 0.03% sodium azide. |
|Other Names||C-reactive protein, C-reactive protein(1-205), CRP, PTX1|
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CRP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.|
|Tissue Location||Found in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
1. Clin Cardiol. 2010 Nov;33(11):708-14. 2. Mol Cell Biochem. 2011 Jan;347(1-2):183-9.
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