|Application ||WB, IHC, FC, ICC, E|
|Description||RAB6B (RAB6B, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB41.;|
|Immunogen||Purified recombinant fragment of human Rab6b (AA: 95-208) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Application Note||ELISA: 1/10000|
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
ICC: 1/200 - 1/1000
FCM: 1/200 - 1/400
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Monoclonal Antibody to Rab6b is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.|
|Cellular Location||Golgi apparatus membrane; Lipid- anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle. Note=Colocalizes with BICD1 at vesicular structures that align along microtubules|
|Tissue Location||Predominantly expressed in brain.|
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Provided below are standard protocols that you may find useful for product applications.
1.Exp Cell Res. 2007 Oct 1;313(16):3408-20. ; 2.J Cell Sci. 2000 Aug;113 ( Pt 15):2725-35.;
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