|Application ||WB, E|
|Other Accession||Q5FVK8, Q8BIX3, Q5EA92, NP_689529.1|
|Antigen Region||228-257 aa|
|Other Names||ARL14 effector protein, ARF7 effector protein, ARL14EP, ARF7EP, C11orf46|
|Target/Specificity||This C11orf46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the C-terminal region of human C11orf46.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||C11orf46 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.|
|Tissue Location||Expressed in the immune system. EMBL; AK096287; BAC04747.1; -; mRNA EMBL; BX647617; CAI46092.1; -; mRNA EMBL; BC047775; AAH47775.1; -; mRNA CCDS; CCDS7869.1; - RefSeq; NP_689529.1; NM_152316.2 UniGene; Hs.502208; - ProteinModelPortal; Q8N8R7; - SMR; Q8N8R7; - BioGrid; 125690; 9 IntAct; Q8N8R7; 8 STRING; 9606.ENSP00000282032; - iPTMnet; Q8N8R7; - PhosphoSitePlus; Q8N8R7; - BioMuta; ARL14EP; - DMDM; 74729511; - EPD; Q8N8R7; - MaxQB; Q8N8R7; - PaxDb; Q8N8R7; - PeptideAtlas; Q8N8R7; - PRIDE; Q8N8R7; - ProteomicsDB; 72456; - DNASU; 120534; - Ensembl; ENST00000282032; ENSP00000282032; ENSG00000152219 GeneID; 120534; - KEGG; hsa:120534; - UCSC; uc001mso.2; human CTD; 120534; - DisGeNET; 120534; - EuPathDB; HostDB:ENSG00000152219.4; - GeneCards; ARL14EP; - H-InvDB; HIX0017336; - HGNC; HGNC:26798; ARL14EP HPA; HPA039634; - HPA; HPA048127; - MIM; 612295; gene neXtProt; NX_Q8N8R7; - OpenTargets; ENSG00000152219; - PharmGKB; PA142672291; - eggNOG; KOG4850; Eukaryota eggNOG; ENOG4111QTN; LUCA GeneTree; ENSGT00510000047210; - HOGENOM; HOG000232178; - HOVERGEN; HBG055275; - InParanoid; Q8N8R7; - OMA; QFANPGR; - OrthoDB; EOG091G0X7Y; - PhylomeDB; Q8N8R7; - TreeFam; TF333216; - ChiTaRS; ARL14EP; human GenomeRNAi; 120534; - PRO; PR:Q8N8R7; - Proteomes; UP000005640; Chromosome 11 Bgee; ENSG00000152219; - CleanEx; HS_C11orf46; - ExpressionAtlas; Q8N8R7; baseline and differential Genevisible; Q8N8R7; HS GO; GO:0005829; C:cytosol; IDA:HPA GO; GO:0005925; C:focal adhesion; IDA:HPA GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA GO; GO:0005730; C:nucleolus; IDA:HPA GO; GO:0005634; C:nucleus; IDA:HPA GO; GO:0005886; C:plasma membrane; IDA:HPA InterPro; IPR029264; ARF7EP_C InterPro; IPR026515; ARL14EP PANTHER; PTHR23080:SF72; PTHR23080:SF72; 1 Pfam; PF14949; ARF7EP_C; 1 1: Evidence at protein level; Acetylation; Complete proteome; Cytoplasm; Isopeptide bond; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation CHAIN 1 260 ARL14 effector protein /FTId=PRO_0000251892 COMPBIAS 209 237 Cys-rich MOD_RES 1 1 N-acetylmethionine MOD_RES 183 183 Phosphoserine CROSSLNK 177 177 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) VARIANT 180 180 T -> P (in dbSNP:rs7940297) /FTId=VAR_033740 CONFLICT 88 88 K -> KK (in Ref. 2; CAI46092) CONFLICT 245 245 Q -> QK (in Ref. 2; CAI46092) SEQUENCE 260 AA; 29338 MW; 18B70E7DB57B3252 CRC64; MMDPCSVGVQ LRTTNECHKT YYTRHTGFKT LQELSSNDML LLQLRTGMTL SGNNTICFHH VKIYIDRFED LQKSCCDPFN IHKKLAKKNL HVIDLDDATF LSAKFGRQLV PGWKLCPKCT QIINGSVDVD TEDRQKRKPE SDGRTAKALR SLQFTNPGRQ TEFAPETGKR EKRRLTKNAT AGSDRQVIPA KSKVYDSQGL LIFSGMDLCD CLDEDCLGCF YACPACGSTK CGAECRCDRK WLYEQIEIEG GEIIHNKHAG|
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