- CITATIONS: 2
|Application ||WB, IHC-P, FC, E|
|Calculated MW||40222 Da|
|Antigen Region||319-348 aa|
|Other Names||Alcohol dehydrogenase 4, Alcohol dehydrogenase class II pi chain, ADH4|
|Target/Specificity||This ADH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-348 amino acids from the C-terminal region of human ADH4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ADH4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
Provided below are standard protocols that you may find useful for product applications.
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
Pochareddy, S., et al. Gene 460 (1-2), 1-7 (2010) :
Preuss, U.W., et al. Addict Biol (2010) In press :
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Rainero, I., et al. Headache 50(1):92-98(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
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