|Application ||WB, FC, E|
|Other Accession||Q19A41, NP_619638.1|
|Calculated MW||33094 Da|
|Antigen Region||254-283 aa|
|Other Names||Krueppel-like factor 14, Basic transcription element-binding protein 5, BTE-binding protein 5, Transcription factor BTEB5, KLF14, BTEB5|
|Target/Specificity||This KLF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-283 amino acids from the C-terminal region of human KLF14.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLF14 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Kruppel-like family of transcription factors. The gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. Expression of this gene is induced by TGF-beta, and the protein represses TGF-beta receptor II expression. The protein functions as part of a transcriptional co-repressor complex that also contains the transcriptional regulator SIN3A and histone deacetylase 2.
Voight, B.F., et al. Nat. Genet. 42(7):579-589(2010) Chasman, D.I., et al. PLoS Genet. 5 (11), E1000730 (2009) : Stacey, S.N., et al. Nat. Genet. 41(8):909-914(2009) Truty, M.J., et al. J. Biol. Chem. 284(10):6291-6300(2009) Parker-Katiraee, L., et al. PLoS Genet. 3 (5), E65 (2007) :
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