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>   home   >   Products   >   Primary Antibodies   >   TDRD7 Antibody (C-term)   

TDRD7 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TDRD7 Antibody (C-term) AP10982b
    TDRD7 Antibody (C-term) (Cat. #AP10982b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TDRD7 antibody detected the TDRD7 protein (arrow).
  • WB - TDRD7 Antibody (C-term) AP10982b
    TDRD7 Antibody (C-term) (Cat. #AP10982b) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the TDRD7 antibody detected the TDRD7 protein (arrow).
  • IHC-P - TDRD7 Antibody (C-term) AP10982b
    TDRD7 antibody (C-term) (Cat. #AP10982b) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TDRD7 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - TDRD7 Antibody (C-term) AP10982b
    TDRD7 Antibody (C-term) (Cat. #AP10982b) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NHU6
Other Accession Q9R1R4, A6QLE1, NP_055105.2
Reactivity Human, Mouse
Predicted Bovine, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 123586 Da
Antigen Region 807-835 aa
Additional Information
Gene ID 23424
Other Names Tudor domain-containing protein 7, PCTAIRE2-binding protein, Tudor repeat associator with PCTAIRE-2, Trap, TDRD7, PCTAIRE2BP
Target/Specificity This TDRD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 807-835 amino acids from the C-terminal region of human TDRD7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTDRD7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TDRD7
Function Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
Cellular Location Cytoplasm. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By similarity).
Citations (0)

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TDRD7, also known as Tudor domain containing protein 7, is a component of chromatoid bodies in spermatids (named processing bodies or P-bodies in somatic cells). It is found in a mRNP complex together with TDRD1, TDRD6 and DDX4. It is also found in a complex with CABLES1, PCTK2 and PIWIL1. TDRD7 has been shown to interact with histone H3 tri-methylated at K9 in vitro.


Lim, J., et al. Cell 125(4):801-814(2006)
Conte, N., et al. Oncogene 22(50):8102-8116(2003)
Lauffart, B., et al. Biochem. J. 363 (PT 1), 195-200 (2002) :
Yamochi, T., et al. Biochem. Biophys. Res. Commun. 286(5):1045-1050(2001)
Hirose, T., et al. Eur. J. Biochem. 267(7):2113-2121(2000)

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Cat# AP10982b
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