|Application ||WB, IHC-P, FC, E|
|Calculated MW||109244 Da|
|Antigen Region||899-930 aa|
|Other Names||Glutamyl aminopeptidase, EAP, Aminopeptidase A, AP-A, Differentiation antigen gp160, CD249, ENPEP|
|Target/Specificity||This ENPEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 899-930 amino acids from the C-terminal region of human ENPEP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ENPEP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates central hypertension through its calcium- modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in choriocarcinoma cancer cell lines (at protein level) (PubMed:10692253). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
ENPEP appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Perez, I., et al. Head Neck 31(10):1335-1340(2009)
Sevalle, J., et al. J. Neurochem. 109(1):248-256(2009)
Teranishi, J., et al. Prostate 68(15):1666-1673(2008)
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