|Application ||WB, E|
|Other Accession||NP_001171626.1, NP_001171623.1, NP_064588.1|
|Calculated MW||58419 Da|
|Antigen Region||19-48 aa|
|Other Names||Matrix extracellular phosphoglycoprotein, Osteoblast/osteocyte factor 45, OF45, MEPE|
|Target/Specificity||This MEPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human MEPE.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MEPE Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes renal phosphate excretion and modulates mineralization.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Expressed by osteoblasts. Secreted from oncogenic hypophosphataemic tumors|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
MEPE seems to play a role in mineralization.
Boskey, A.L., et al. Calcif. Tissue Int. 86(1):42-46(2010)
Pereira, R.C., et al. Bone 45(6):1161-1168(2009)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
Marks, J., et al. J. Am. Soc. Nephrol. 19(12):2313-2320(2008)
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