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TBCEL Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TBCEL Antibody (C-term) AP12428b
    TBCEL Antibody (C-term) (Cat. #AP12428b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TBCEL antibody detected the TBCEL protein (arrow).
  • IHC-P - TBCEL Antibody (C-term) AP12428b
    TBCEL Antibody (C-term) (Cat. #AP12428b)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TBCEL Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5QJ74
Other Accession Q5PQJ7, Q8C5W3, NP_689928.3, NP_001123519.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 385-413 aa
Additional Information
Other Names Tubulin-specific chaperone cofactor E-like protein, EL, Leucine-rich repeat-containing protein 35, TBCEL, LRRC35
Target/Specificity This TBCEL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-413 amino acids from the C-terminal region of human TBCEL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBCEL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LRRC35
Function Acts as a regulator of tubulin stability.
Cellular Location Cytoplasm, cytoskeleton.
Tissue Location Abundantly expressed in testis, but is also present in several tissues at a much lower level EMBL; AY398644; AAR27875.1; -; mRNA EMBL; AK295673; BAG58531.1; -; mRNA EMBL; CH471065; EAW67514.1; -; Genomic_DNA EMBL; BC120988; AAI20989.1; -; mRNA CCDS; CCDS31692.1; - RefSeq; NP_001123519.1; NM_001130047.1 RefSeq; NP_689928.3; NM_152715.3 RefSeq; XP_016872815.1; XM_017017326.1 UniGene; Hs.504136; - UniGene; Hs.720282; - ProteinModelPortal; Q5QJ74; - BioGrid; 128592; 3 IntAct; Q5QJ74; 6 STRING; 9606.ENSP00000403925; - iPTMnet; Q5QJ74; - PhosphoSitePlus; Q5QJ74; - BioMuta; TBCEL; - DMDM; 215273924; - EPD; Q5QJ74; - MaxQB; Q5QJ74; - PaxDb; Q5QJ74; - PeptideAtlas; Q5QJ74; - PRIDE; Q5QJ74; - ProteomicsDB; 63619; - Ensembl; ENST00000422003; ENSP00000403925; ENSG00000154114 Ensembl; ENST00000529397; ENSP00000437184; ENSG00000154114 GeneID; 219899; - KEGG; hsa:219899; - UCSC; uc001pxo.4; human CTD; 219899; - DisGeNET; 219899; - EuPathDB; HostDB:ENSG00000154114.12; - GeneCards; TBCEL; - H-InvDB; HIX0010204; - HGNC; HGNC:28115; TBCEL HPA; HPA038593; - HPA; HPA038594; - MIM; 610451; gene neXtProt; NX_Q5QJ74; - OpenTargets; ENSG00000154114; - PharmGKB; PA162405374; - eggNOG; KOG2982; Eukaryota eggNOG; ENOG41103AE; LUCA GeneTree; ENSGT00530000063405; - HOGENOM; HOG000004866; - HOVERGEN; HBG082881; - InParanoid; Q5QJ74; - KO; K22449; - OMA; ECEFENA; - OrthoDB; EOG091G08JF; - PhylomeDB; Q5QJ74; - TreeFam; TF320819; - ChiTaRS; TBCEL; human GenomeRNAi; 219899; - PRO; PR:Q5QJ74; - Proteomes; UP000005640; Chromosome 11 Bgee; ENSG00000154114; - CleanEx; HS_TBCEL; - ExpressionAtlas; Q5QJ74; baseline and differential Genevisible; Q5QJ74; HS GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell Gene3D;; -; 2 InterPro; IPR032675; LRR_dom_sf InterPro; IPR029071; Ubiquitin-like_domsf InterPro; IPR000626; Ubiquitin_dom Pfam; PF14560; Ubiquitin_2; 1 SUPFAM; SSF54236; SSF54236; 1 PROSITE; PS50053; UBIQUITIN_2; 1 1: Evidence at protein level; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Leucine-rich repeat; Phosphoprotein; Reference proteome; Repeat CHAIN 1 424 Tubulin-specific chaperone cofactor E- like protein /FTId=PRO_0000239668 REPEAT 73 98 LRR 1 REPEAT 99 123 LRR 2 REPEAT 124 147 LRR 3 REPEAT 150 172 LRR 4 REPEAT 173 197 LRR 5 REPEAT 199 224 LRR 6 REPEAT 226 250 LRR 7 DOMAIN 262 303 LRRCT DOMAIN 334 424 Ubiquitin-like. {ECO:0000255|PROSITE- ProRule:PRU00214} COILED 349 375 MOD_RES 18 18 Phosphoserine {ECO:0000250|UniProtKB:Q8C5W3} MOD_RES 41 41 Phosphoserine CONFLICT 226 226 F -> V (in Ref. 1; AAR27875) CONFLICT 236 236 K -> R (in Ref. 1; AAR27875) CONFLICT 334 334 A -> T (in Ref. 1; AAR27875) SEQUENCE 424 AA; 48195 MW; F9057405EB096A9E CRC64; MDQPSGRSFM QVLCEKYSPE NFPYRRGPGM GVHVPATPQG SPMKDRLNLP SVLVLNSCGI TCAGDEKEIA AFCAHVSELD LSDNKLEDWH EVSKIVSNVP QLEFLNLSSN PLNLSVLERT CAGSFSGVRK LVLNNSKASW ETVHMILQEL PDLEELFLCL NDYETVSCPS ICCHSLKLLH ITDNNLQDWT EIRKLGVMFP SLDTLVLANN HLNAIEEPDD SLARLFPNLR SISLHKSGLQ SWEDIDKLNS FPKLEEVRLL GIPLLQPYTT EERRKLVIAR LPSVSKLNGS VVTDGEREDS ERFFIRYYVD VPQEEVPFRY HELITKYGKL EPLAEVDLRP QSSAKVEVHF NDQVEEMSIR LDQTVAELKK QLKTLVQLPT SNMLLYYFDH EAPFGPEEMK YSSRALHSFG IRDGDKIYVE SKTK
Research Areas
Citations (0)

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TBCEL acts as a regulator of tubulin stability.


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Sellin, M.E., et al. Exp. Cell Res. 314(6):1367-1377(2008)
Bartolini, F., et al. J. Cell. Sci. 118 (PT 6), 1197-1207 (2005) :

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$ 325.00
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Cat# AP12428b
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