|Application ||WB, IHC-P, E|
|Other Accession||NP_659437.3, NP_001154901.1|
|Calculated MW||52211 Da|
|Antigen Region||137-165 aa|
|Other Names||Ran-binding protein 3-like, RANBP3L|
|Target/Specificity||This RANBP3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the Central region of human RANBP3L.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RANBP3L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner.|
|Cellular Location||Nucleus. Cytoplasm|
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The function of this protein remains unknown.
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