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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Mark3 Antibody (C-term)   

Mouse Mark3 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Mark3 Antibody (C-term) AP14270B
    Mouse Mark3 Antibody (C-term) (Cat. #AP14270b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Mark3 antibody detected the Mark3 protein (arrow).
  • WB - Mouse Mark3 Antibody (C-term) AP14270B
    Mouse Mark3 Antibody (C-term) (Cat. #AP14270b) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the Mark3 antibody detected the Mark3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q03141
Other Accession P27448, NP_067491.2, NP_073712.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 84390 Da
Antigen Region 608-636 aa
Additional Information
Gene ID 17169
Other Names MAP/microtubule affinity-regulating kinase 3, ELKL motif kinase 2, EMK-2, MPK-10, Mark3, Emk2, Mpk10
Target/Specificity This Mouse Mark3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 608-636 amino acids from the C-terminal region of mouse Mark3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Mark3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mark3
Synonyms Emk2, Mpk10
Function Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAPT/TAU, MAP2 and MAP4. Phosphorylates CDC25C. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:P27448}; Peripheral membrane protein {ECO:0000250|UniProtKB:P27448}. Cell projection, dendrite {ECO:0000250|UniProtKB:P27448}. Cytoplasm {ECO:0000250|UniProtKB:P27448}
Research Areas
Citations (0)

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Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C (By similarity).


Lennerz, J.K., et al. Mol. Cell. Biol. 30(21):5043-5056(2010)
Schwarz, T., et al. Biochem. Biophys. Res. Commun. 394(4):890-895(2010)
Hezel, A.F., et al. Mol. Cell. Biol. 28(7):2414-2425(2008)
Wang, C., et al. Acta Pharmacol. Sin. 28(3):334-338(2007)
Tochio, N., et al. Protein Sci. 15(11):2534-2543(2006)

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$ 325.00
$ 109.00
Cat# AP14270B
Availability: In Stock
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