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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   HN1 Antibody (Center)   

HN1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HN1 Antibody (Center) AP14797c
    HN1 Antibody (Center) (Cat. #AP14797c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the HN1 antibody detected the HN1 protein (arrow).
  • IF - HN1 Antibody (Center) AP14797c
    Confocal immunofluorescent analysis of HN1 Antibody (Center)(Cat#AP14797c) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
  • FC - HN1 Antibody (Center) AP14797c
    HN1 Antibody (Center) (Cat. #AP14797c) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UK76
Other Accession NP_001002033.1, NP_057269.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 16015 Da
Antigen Region 58-86 aa
Additional Information
Gene ID 51155
Other Names Hematological and neurological expressed 1 protein, Androgen-regulated protein 2, Hematological and neurological expressed 1 protein, N-terminally processed, HN1, ARM2
Target/Specificity This HN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human HN1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name JPT1 (HGNC:14569)
Function Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR- signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
Cellular Location Nucleus. Cytoplasm
Tissue Location Expressed in testis, skeletal muscle, thymus, prostate, colon, peripheral blood cells, brain and placenta
Research Areas
Citations (0)

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HN1 belongs to the HN1 family.


Laughlin, K.M., et al. Pathol. Oncol. Res. 15(3):437-444(2009)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Zougman, A., et al. J. Proteome Res. 5(4):925-934(2006)
Zhou, G., et al. Gene 331, 115-123 (2004) :

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$ 325.00
$ 109.00
Cat# AP14797c
Availability: In Stock
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