|Application ||WB, E|
|Other Accession||NP_001158164.1, NP_062813.2|
|Calculated MW||41525 Da|
|Antigen Region||333-361 aa|
|Other Names||Leukotriene B4 receptor 2, LTB4-R 2, LTB4-R2, LTB4 receptor JULF2, Leukotriene B4 receptor BLT2, Seven transmembrane receptor BLTR2, LTB4R2, BLT2R, BLTR2|
|Target/Specificity||This LTB4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the C-terminal region of human LTB4R2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LTB4R2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
Kim, G.Y., et al. J. Immunol. 184(7):3946-3954(2010)
Ryu, H.C., et al. J. Invest. Dermatol. 130(4):1095-1106(2010)
Choi, J.A., et al. Carcinogenesis 31(4):543-551(2010)
Cho, K.J., et al. Am. J. Respir. Cell Mol. Biol. 42(3):294-303(2010)
Arcemisbehere, L., et al. J. Biol. Chem. 285(9):6337-6347(2010)
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