|Application ||WB, E|
|Other Accession||P84096, NP_001656.2|
|Calculated MW||21309 Da|
|Antigen Region||99-128 aa|
|Other Names||Rho-related GTP-binding protein RhoG, RHOG, ARHG|
|Target/Specificity||This RHOG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-128 amino acids from the C-terminal region of human RHOG.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RHOG Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
ARHG is a member of the RAS superfamily of genes, which encode GTP-binding proteins that act in the pathway of signal transduction and play a key role in the regulation of cellular functions.
Hiramoto-Yamaki, N., et al. J. Cell Biol. 190(3):461-477(2010)
Segat, L., et al. Vaccine 28(10):2201-2206(2010)
Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) :
Roppenser, B., et al. J. Cell. Sci. 122 (PT 5), 696-705 (2009) :
van Buul, J.D., et al. J. Cell Biol. 178(7):1279-1293(2007)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.