|Application ||WB, E|
|Other Accession||Q8R5F8, NP_573441.2, NP_060199.3|
|Calculated MW||80251 Da|
|Antigen Region||1-30 aa|
|Other Names||Epidermal growth factor receptor kinase substrate 8-like protein 1, EPS8-like protein 1, Epidermal growth factor receptor pathway substrate 8-related protein 1, EPS8-related protein 1, EPS8L1, DRC3, EPS8R1|
|Target/Specificity||This EPS8L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EPS8L1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EPS8L1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.|
|Tissue Location||Detected in placenta.|
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Provided below are standard protocols that you may find useful for product applications.
EPS8L1 is a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Offenhauser, N., et al. Mol. Biol. Cell 15(1):91-98(2004)
Tocchetti, A., et al. Genomics 81(2):234-244(2003)
Wu, K., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 16(5):325-327(1999)
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