Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   NACC2 Antibody (C-term)   

NACC2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NACC2 Antibody (C-term) AP16720b
    NACC2 Antibody (C-term) (Cat. #AP16720b) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NACC2 antibody detected the NACC2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96BF6
Other Accession NP_653254.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 473-502 aa
Additional Information
Other Names Nucleus accumbens-associated protein 2, NAC-2, BTB/POZ domain-containing protein 14A, Repressor with BTB domain and BEN domain, NACC2, BTBD14A, NAC2, RBB
Target/Specificity This NACC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the C-terminal region of human NACC2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNACC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NACC2
Synonyms BTBD14A, NAC2, RBB
Function Functions as a transcriptional repressor through its association with the NuRD complex. Recruits the NuRD complex to the promoter of MDM2, leading to the repression of MDM2 transcription and subsequent stability of p53/TP53.
Cellular Location Nucleus. Note=Predominantly associated with chromatin EMBL; AL591038; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL355574; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC015649; AAH15649.1; -; mRNA CCDS; CCDS6993.1; - RefSeq; NP_653254.1; NM_144653.4 RefSeq; XP_011516523.1; XM_011518221.2 UniGene; Hs.112895; - UniGene; Hs.736561; - ProteinModelPortal; Q96BF6; - SMR; Q96BF6; - BioGrid; 126501; 13 IntAct; Q96BF6; 2 MINT; Q96BF6; - STRING; 9606.ENSP00000277554; - iPTMnet; Q96BF6; - PhosphoSitePlus; Q96BF6; - BioMuta; NACC2; - DMDM; 74751767; - EPD; Q96BF6; - MaxQB; Q96BF6; - PaxDb; Q96BF6; - PeptideAtlas; Q96BF6; - PRIDE; Q96BF6; - ProteomicsDB; 76074; - DNASU; 138151; - Ensembl; ENST00000277554; ENSP00000277554; ENSG00000148411 Ensembl; ENST00000371753; ENSP00000360818; ENSG00000148411 GeneID; 138151; - KEGG; hsa:138151; - UCSC; uc004cgv.4; human CTD; 138151; - DisGeNET; 138151; - EuPathDB; HostDB:ENSG00000148411.7; - GeneCards; NACC2; - HGNC; HGNC:23846; NACC2 HPA; HPA047924; - HPA; HPA052962; - MIM; 615786; gene neXtProt; NX_Q96BF6; - OpenTargets; ENSG00000148411; - PharmGKB; PA164723421; - eggNOG; KOG1721; Eukaryota eggNOG; COG5048; LUCA GeneTree; ENSGT00760000119063; - HOGENOM; HOG000231834; - HOVERGEN; HBG052875; - InParanoid; Q96BF6; - KO; K10486; - OMA; SVPPACF; - OrthoDB; EOG091G05RI; - PhylomeDB; Q96BF6; - TreeFam; TF331184; - ChiTaRS; NACC2; human GenomeRNAi; 138151; - PRO; PR:Q96BF6; - Proteomes; UP000005640; Chromosome 9 Bgee; ENSG00000148411; - CleanEx; HS_NACC2; - ExpressionAtlas; Q96BF6; baseline and differential Genevisible; Q96BF6; HS GO; GO:0005739; C:mitochondrion; IDA:HPA GO; GO:0016604; C:nuclear body; ISS:UniProtKB GO; GO:0000790; C:nuclear chromatin; IDA:BHF-UCL GO; GO:0005730; C:nucleolus; IDA:HPA GO; GO:0005634; C:nucleus; IDA:UniProtKB GO; GO:0004407; F:histone deacetylase activity; IDA:BHF-UCL GO; GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL GO; GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL GO; GO:0044877; F:protein-containing complex binding; IPI:BHF-UCL GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IDA:BHF-UCL GO; GO:0001078; F:transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IDA:BHF-UCL GO; GO:0034629; P:cellular protein-containing complex localization; IDA:BHF-UCL GO; GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL GO; GO:1900477; P:negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB GO; GO:1902231; P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; IDA:BHF-UCL GO; GO:0010608; P:posttranscriptional regulation of gene expression; IMP:BHF-UCL GO; GO:0051260; P:protein homooligomerization; IDA:UniProtKB GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW InterPro; IPR018379; BEN_domain InterPro; IPR000210; BTB/POZ_dom InterPro; IPR011333; SKP1/BTB/POZ_sf Pfam; PF10523; BEN; 1 Pfam; PF00651; BTB; 1 SMART; SM01025; BEN; 1 SMART; SM00225; BTB; 1 SUPFAM; SSF54695; SSF54695; 1 PROSITE; PS51457; BEN; 1 PROSITE; PS50097; BTB; 1 1: Evidence at protein level; Complete proteome; Isopeptide bond; Nucleus; Reference proteome; Repressor; Transcription; Transcription regulation; Ubl conjugation CHAIN 1 587 Nucleus accumbens-associated protein 2 /FTId=PRO_0000263668 DOMAIN 30 94 BTB. {ECO:0000255|PROSITE- ProRule:PRU00037} DOMAIN 351 448 BEN. {ECO:0000255|PROSITE- ProRule:PRU00784} CROSSLNK 174 174 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) CROSSLNK 217 217 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) CROSSLNK 299 299 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) CROSSLNK 429 429 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) CROSSLNK 456 456 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) SEQUENCE 587 AA; 62837 MW; BE1EF06B210EEDBA CRC64; MSQMLHIEIP NFGNTVLGCL NEQRLLGLYC DVSIVVKGQA FKAHRAVLAA SSLYFRDLFS GNSKSAFELP GSVPPACFQQ ILSFCYTGRL TMTASEQLVV MYTAGFLQIQ HIVERGTDLM FKVSSPHCDS QTAVIEDAGS EPQSPCNQLQ PAAAAAAPYV VSPSVPIPLL TRVKHEAMEL PPAGPGLAPK RPLETGPRDG VAVAAGAAVA AGTAPLKLPR VSYYGVPSLA TLIPGIQQMP YPQGERTSPG ASSLPTTDSP TSYHNEEDEE DDEAYDTMVE EQYGQMYIKA SGSYAVQEKP EPVPLESRSC VLIRRDLVAL PASLISQIGY RCHPKLYSEG DPGEKLELVA GSGVYITRGQ LMNCHLCAGV KHKVLLRRLL ATFFDRNTLA NSCGTGIRSS TSDPSRKPLD SRVLNAVKLY CQNFAPSFKE SEMNVIAADM CTNARRVRKR WLPKIKSMLP EGVEMYRTVM GSAAASVPLD PEFPPAAAQV FEQRIYAERR GDAATIVALR TDAVNVDLSA AANPAFDAGE EVDGAGSVIQ EVAAPEPLPA DGQSPPQPFE QGGGGPSRPQ TPAAAARRPE GTYAGTL
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Humphray, S.J., et al. Nature 429(6990):369-374(2004)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 325.00
$ 109.00
Cat# AP16720b
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions