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SSBP3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SSBP3 Antibody (Center) AP17077c
    SSBP3 Antibody (Center) (Cat. #AP17077c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SSBP3 antibody detected the SSBP3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BWW4
Other Accession Q9D032, Q98948, NP_001009955.1, NP_060540.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 166-192 aa
Additional Information
Other Names Single-stranded DNA-binding protein 3, Sequence-specific single-stranded-DNA-binding protein, SSBP3, SSDP, SSDP1
Target/Specificity This SSBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-192 amino acids from the Central region of human SSBP3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSBP3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSBP3
Synonyms SSDP, SSDP1
Function May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region.
Cellular Location Nucleus.
Tissue Location Highly expressed in all hematopoietic tissues, including spleen, lymph node, peripheral blood, bone marrow, thymus, and fetal liver, with highest expression in thymus and fetal liver. Expression is also high in heart, brain, kidney, and skeletal muscle EMBL; AY026310; AAK21984.1; -; Genomic_DNA EMBL; AY026293; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026294; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026295; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026296; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026297; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026298; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026299; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026300; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026301; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026302; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026303; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026304; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026305; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026306; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026307; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026308; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026309; AAK21984.1; JOINED; Genomic_DNA EMBL; AY026310; AAK21985.1; -; Genomic_DNA EMBL; AY026293; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026294; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026295; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026296; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026297; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026299; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026300; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026301; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026302; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026303; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026304; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026305; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026306; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026307; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026308; AAK21985.1; JOINED; Genomic_DNA EMBL; AY026309; AAK21985.1; JOINED; Genomic_DNA EMBL; AF500116; AAM22101.1; -; mRNA EMBL; AK289474; BAF82163.1; -; mRNA EMBL; CH471059; EAX06692.1; -; Genomic_DNA EMBL; AL035415; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL161644; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC003605; AAH03605.1; -; mRNA EMBL; BC066365; AAH66365.1; -; mRNA CCDS; CCDS30726.1; -. [Q9BWW4-2] CCDS; CCDS590.1; -. [Q9BWW4-3] CCDS; CCDS591.1; -. [Q9BWW4-1] RefSeq; NP_001009955.1; NM_001009955.3. [Q9BWW4-2] RefSeq; NP_060540.2; NM_018070.4. [Q9BWW4-3] RefSeq; NP_663768.1; NM_145716.3. [Q9BWW4-1] UniGene; Hs.476706; - UniGene; Hs.658676; - ProteinModelPortal; Q9BWW4; - BioGrid; 117175; 37 DIP; DIP-48897N; - IntAct; Q9BWW4; 14 STRING; 9606.ENSP00000360371; - iPTMnet; Q9BWW4; - PhosphoSitePlus; Q9BWW4; - DMDM; 27734581; - EPD; Q9BWW4; - MaxQB; Q9BWW4; - PaxDb; Q9BWW4; - PeptideAtlas; Q9BWW4; - PRIDE; Q9BWW4; - ProteomicsDB; 79330; - ProteomicsDB; 79331; -. [Q9BWW4-2] ProteomicsDB; 79332; -. [Q9BWW4-3] DNASU; 23648; - Ensembl; ENST00000357475; ENSP00000350067; ENSG00000157216. [Q9BWW4-3] Ensembl; ENST00000371319; ENSP00000360370; ENSG00000157216. [Q9BWW4-2] Ensembl; ENST00000371320; ENSP00000360371; ENSG00000157216. [Q9BWW4-1] GeneID; 23648; - KEGG; hsa:23648; - UCSC; uc001cxe.5; human. [Q9BWW4-1] CTD; 23648; - DisGeNET; 23648; - EuPathDB; HostDB:ENSG00000157216.15; - GeneCards; SSBP3; - HGNC; HGNC:15674; SSBP3 MIM; 607390; gene neXtProt; NX_Q9BWW4; - OpenTargets; ENSG00000157216; - PharmGKB; PA38017; - eggNOG; KOG4594; Eukaryota eggNOG; ENOG410XPQX; LUCA GeneTree; ENSGT00390000009187; - HOGENOM; HOG000037785; - HOVERGEN; HBG068487; - InParanoid; Q9BWW4; - OMA; HNPNSMM; - OrthoDB; EOG091G111C; - PhylomeDB; Q9BWW4; - TreeFam; TF318961; - ChiTaRS; SSBP3; human GeneWiki; SSBP3; - GenomeRNAi; 23648; - PRO; PR:Q9BWW4; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000157216; - CleanEx; HS_SSBP3; - ExpressionAtlas; Q9BWW4; baseline and differential Genevisible; Q9BWW4; HS GO; GO:0005634; C:nucleus; IBA:GO_Central GO; GO:0032991; C:protein-containing complex; IEA:Ensembl GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IBA:GO_Central GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro GO; GO:0001077; F:transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IBA:GO_Central GO; GO:0060322; P:head development; IBA:GO_Central GO; GO:0060323; P:head morphogenesis; IEA:Ensembl GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IEA:Ensembl GO; GO:0021547; P:midbrain-hindbrain boundary initiation; IEA:Ensembl GO; GO:2000744; P:positive regulation of anterior head development; IEA:Ensembl GO; GO:0008284; P:positive regulation of cell proliferation; IEA:Ensembl GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central GO; GO:0021501; P:prechordal plate formation; IEA:Ensembl GO; GO:0065003; P:protein-containing complex assembly; IEA:Ensembl InterPro; IPR006594; LisH InterPro; IPR008116; SSDP_DNA-bd PRINTS; PR01743; SSDNABINDING SMART; SM00667; LisH; 1 PROSITE; PS50896; LISH; 1 1: Evidence at protein level; Acetylation; Alternative splicing; Complete proteome; DNA-binding; Methylation; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation CHAIN 1 388 Single-stranded DNA-binding protein 3 /FTId=PRO_0000123828 DOMAIN 16 48 LisH. {ECO:0000255|PROSITE- ProRule:PRU00126} COMPBIAS 98 319 Pro-rich COMPBIAS 158 369 Gly-rich MOD_RES 1 1 N-acetylmethionine MOD_RES 155 155 Asymmetric dimethylarginine MOD_RES 161 161 Asymmetric dimethylarginine MOD_RES 165 165 Asymmetric dimethylarginine MOD_RES 347 347 Phosphoserine MOD_RES 352 352 Phosphoserine MOD_RES 355 355 Phosphoserine {ECO:0000250|UniProtKB:Q9D032} MOD_RES 360 360 Phosphothreonine MOD_RES 381 381 Phosphoserine MOD_RES 387 387 Phosphoserine VAR_SEQ 123 149 Missing (in isoform 2) /FTId=VSP_006260 VAR_SEQ 150 169 Missing (in isoform 3) {ECO:0000303|PubMed:15489334, ECO:0000303|Ref.2} /FTId=VSP_006261 SEQUENCE 388 AA; 40421 MW; DBBB169D4EE10536 CRC64; MFAKGKGSAV PSDGQAREKL ALYVYEYLLH VGAQKSAQTF LSEIRWEKNI TLGEPPGFLH SWWCVFWDLY CAAPERRDTC EHSSEAKAFH DYSAAAAPSP VLGNIPPNDG MPGGPIPPGF FQGPPGSQPS PHAQPPPHNP SSMMGPHSQP FMSPRYAGGP RPPIRMGNQP PGGVPGTQPL LPNSMDPTRQ QGHPNMGGSM QRMNPPRGMG PMGPGPQNYG SGMRPPPNSL GPAMPGINMG PGAGRPWPNP NSANSIPYSS SSPGTYVGPP GGGGPPGTPI MPSPADSTNS SDNIYTMINP VPPGGSRSNF PMGPGSDGPM GGMGGMEPHH MNGSLGSGDI DGLPKNSPNN ISGISNPPGT PRDDGELGGN FLHSFQNDNY SPSMTMSV
Citations (0)

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SSBP3 may be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region (By similarity).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Dey-Guha, I., et al. J. Cell. Biochem. 103(6):1856-1865(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Wu, L. Biochem. Biophys. Res. Commun. 339(3):977-984(2006)

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$ 325.00
$ 109.00
Cat# AP17077c
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