|Application ||WB, E|
|Other Accession||P62907, P53026, Q4R5P3, Q5E9E6, NP_009035.3|
|Predicted||Bovine, Monkey, Mouse, Rat|
|Calculated MW||24831 Da|
|Antigen Region||3-31 aa|
|Other Names||60S ribosomal protein L10a, CSA-19, Neural precursor cell expressed developmentally down-regulated protein 6, NEDD-6, RPL10A, NEDD6|
|Target/Specificity||This RPL10A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-31 amino acids from the N-terminal region of human RPL10A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RPL10A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the large ribosomal subunit.|
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Provided below are standard protocols that you may find useful for product applications.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Mazumder, B., et al. Cell 115(2):187-198(2003)
Odintsova, T.I., et al. J. Protein Chem. 22(3):249-258(2003)
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