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MR1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MR1 Antibody (C-term) AP17332B
    MR1 Antibody (C-term) (Cat. #AP17332b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the MR1 antibody detected the MR1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q95460
Other Accession NP_001181929.1, NP_001181928.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 39366 Da
Antigen Region 312-341 aa
Additional Information
Gene ID 3140
Other Names Major histocompatibility complex class I-related gene protein, MHC class I-related gene protein, Class I histocompatibility antigen-like protein, MR1
Target/Specificity This MR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the C-terminal region of human MR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MR1
Function Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
Cellular Location Cell membrane; Single-pass membrane protein; Extracellular side. Endoplasmic reticulum Isoform 3: Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Note=The larger proportion remains in the ER in an immature state. The subset that reach cell surface does it through a B2M-independent pathway
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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MR1 has antigen presentation function. Involved in the development and expansion of a small population of T cells expressing an invariant T cell receptor alpha chain called mucosal-associated invariant T cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therfore may be involed in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.


Gozalbo-Lopez, B., et al. Histol. Histopathol. 24(11):1439-1449(2009)
Stumpf, A.N., et al. Blood 114(17):3684-3692(2009)
Huang, S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(20):8290-8295(2009)
Aldemir, H. Biochem. Biophys. Res. Commun. 366(2):328-334(2008)
Miley, M.J., et al. J. Immunol. 170(12):6090-6098(2003)

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$ 325.00
$ 109.00
Cat# AP17332B
Availability: In Stock
Bulk Size
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