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>   home   >   Products   >   Primary Antibodies   >   FBXO16 Antibody (C-term)   

FBXO16 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FBXO16 Antibody (C-term) AP17533B
    FBXO16 Antibody (C-term) (Cat. #AP17533b) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the FBXO16 antibody detected the FBXO16 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IX29
Other Accession NP_758954.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 245-272 aa
Additional Information
Other Names F-box only protein 16, FBXO16, FBX16
Target/Specificity This FBXO16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-272 amino acids from the C-terminal region of human FBXO16.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFBXO16 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXO16
Synonyms FBX16
Function Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Tissue Location Expressed in heart, spleen and colon. EMBL; AF453435; AAN76812.1; -; mRNA EMBL; AC025871; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC074986; AAH74986.1; -; mRNA EMBL; BC102026; AAI02027.1; -; mRNA EMBL; BC102027; AAI02028.1; -; mRNA EMBL; BC102028; AAI02029.1; -; mRNA CCDS; CCDS59099.1; -. [Q8IX29-2] CCDS; CCDS6068.1; -. [Q8IX29-1] RefSeq; NP_001245140.1; NM_001258211.1. [Q8IX29-2] RefSeq; NP_758954.1; NM_172366.3. [Q8IX29-1] UniGene; Hs.741522; - ProteinModelPortal; Q8IX29; - SMR; Q8IX29; - BioGrid; 127606; 9 IntAct; Q8IX29; 5 STRING; 9606.ENSP00000369604; - iPTMnet; Q8IX29; - PhosphoSitePlus; Q8IX29; - BioMuta; FBXO16; - DMDM; 30580423; - MaxQB; Q8IX29; - PaxDb; Q8IX29; - PRIDE; Q8IX29; - ProteomicsDB; 70969; - Ensembl; ENST00000380254; ENSP00000369604; ENSG00000214050. [Q8IX29-1] Ensembl; ENST00000518734; ENSP00000429687; ENSG00000214050. [Q8IX29-2] GeneID; 157574; - KEGG; hsa:157574; - UCSC; uc003xgu.5; human. [Q8IX29-1] CTD; 157574; - EuPathDB; HostDB:ENSG00000214050.7; - GeneCards; FBXO16; - H-InvDB; HIX0079005; - HGNC; HGNC:13618; FBXO16 HPA; HPA053955; - HPA; HPA058676; - MIM; 608519; gene neXtProt; NX_Q8IX29; - OpenTargets; ENSG00000214050; - PharmGKB; PA134901223; - eggNOG; ENOG410IQD0; Eukaryota eggNOG; ENOG41102EU; LUCA GeneTree; ENSGT00530000063689; - HOGENOM; HOG000110666; - HOVERGEN; HBG051567; - InParanoid; Q8IX29; - KO; K10299; - PhylomeDB; Q8IX29; - TreeFam; TF328656; - GenomeRNAi; 157574; - PRO; PR:Q8IX29; - Proteomes; UP000005640; Chromosome 8 Bgee; ENSG00000214050; - CleanEx; HS_FBXO16; - ExpressionAtlas; Q8IX29; baseline and differential Genevisible; Q8IX29; HS InterPro; IPR036047; F-box-like_dom_sf InterPro; IPR001810; F-box_dom Pfam; PF12937; F-box-like; 1 SMART; SM00256; FBOX; 1 SUPFAM; SSF81383; SSF81383; 1 PROSITE; PS50181; FBOX; 1 2: Evidence at transcript level; Alternative splicing; Complete proteome; Polymorphism; Reference proteome; Ubl conjugation pathway CHAIN 1 292 F-box only protein 16 /FTId=PRO_0000119896 DOMAIN 86 132 F-box. {ECO:0000255|PROSITE- ProRule:PRU00080} VAR_SEQ 34 45 Missing (in isoform 2) /FTId=VSP_045600 VARIANT 75 75 R -> Q (in dbSNP:rs3735726) /FTId=VAR_020409 VARIANT 254 254 M -> I (in dbSNP:rs1390963) /FTId=VAR_024442 VARIANT 255 255 T -> N (in dbSNP:rs7016831) /FTId=VAR_049041 CONFLICT 254 255 MT -> IN (in Ref. 3; AAI02028) SEQUENCE 292 AA; 34588 MW; 0A7030EFE682EDFD CRC64; MMAFAPPKNT DGPKMQTKMS TWTPLNHQLL NDRVFEERRA LLGKWFDKWT DSQRRRILTG LLERCSLSQQ KFCCRKLQEK IPAEALDFTT KLPRVLSLYI FSFLDPRSLC RCAQVCWHWK NLAELDQLWM LKCLRFNWYI NFSPTPFEQG IWKKHYIQMV KELHITKPKT PPKDGFVIAD VQLVTSNSPE EKQSPLSAFR SSSSLRKKNN SGEKALPPWR SSDKHPTDII RFNYLDNRDP METVQQGRRK RNQMTPDFSR QSHDKKNKLQ DRTRLRKAQS MMSRRNPFPL CP
Citations (0)

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This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class.


Cheng, H., et al. Mol. Cells 14(1):56-59(2002)
Cenciarelli, C., et al. Curr. Biol. 9(20):1177-1179(1999)

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$ 325.00
$ 109.00
Cat# AP17533B
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