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>   home   >   Products   >   Primary Antibodies   >   Developmental Biology   >   TCF15 Antibody (Center)   

TCF15 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TCF15 Antibody (Center) AP18248c
    TCF15 Antibody (Center) (Cat. #AP18248c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TCF15 antibody detected the TCF15 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q12870
Other Accession Q60756, P79782, NP_004600.2
Reactivity Human
Predicted Chicken, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 81-107 aa
Additional Information
Other Names Transcription factor 15, TCF-15, Class A basic helix-loop-helix protein 40, bHLHa40, Paraxis, Protein bHLH-EC2, TCF15, BHLHA40, BHLHEC2
Target/Specificity This TCF15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human TCF15.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTCF15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TCF15
Synonyms BHLHA40, BHLHEC2
Function May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981} EMBL; U08336; AAA19969.1; -; mRNA EMBL; AL133231; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS33432.1; - PIR; A57717; A57717 RefSeq; NP_004600.2; NM_004609.3 UniGene; Hs.437; - ProteinModelPortal; Q12870; - SMR; Q12870; - BioGrid; 112799; 1 STRING; 9606.ENSP00000246080; - iPTMnet; Q12870; - PhosphoSitePlus; Q12870; - BioMuta; TCF15; - DMDM; 116242817; - PaxDb; Q12870; - PeptideAtlas; Q12870; - PRIDE; Q12870; - ProteomicsDB; 58993; - DNASU; 6939; - Ensembl; ENST00000246080; ENSP00000246080; ENSG00000125878 GeneID; 6939; - KEGG; hsa:6939; - UCSC; uc002wdz.4; human CTD; 6939; - DisGeNET; 6939; - EuPathDB; HostDB:ENSG00000125878.5; - GeneCards; TCF15; - HGNC; HGNC:11627; TCF15 HPA; HPA050998; - HPA; HPA060221; - MIM; 601010; gene neXtProt; NX_Q12870; - OpenTargets; ENSG00000125878; - PharmGKB; PA36382; - eggNOG; KOG4029; Eukaryota eggNOG; ENOG411227D; LUCA GeneTree; ENSGT00760000119097; - HOVERGEN; HBG036149; - InParanoid; Q12870; - KO; K09070; - OMA; FAMLRPV; - OrthoDB; EOG091G0RR2; - PhylomeDB; Q12870; - TreeFam; TF315153; - GenomeRNAi; 6939; - PRO; PR:Q12870; - Proteomes; UP000005640; Chromosome 20 Bgee; ENSG00000125878; - CleanEx; HS_TCF15; - Genevisible; Q12870; HS GO; GO:0090575; C:RNA polymerase II transcription factor complex; IEA:Ensembl GO; GO:0003700; F:DNA binding transcription factor activity; TAS:ProtInc GO; GO:0046983; F:protein dimerization activity; IEA:InterPro GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0001077; F:transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0043583; P:ear development; IEA:Ensembl GO; GO:0042755; P:eating behavior; IEA:Ensembl GO; GO:0045198; P:establishment of epithelial cell apical/basal polarity; IEA:Ensembl GO; GO:0060231; P:mesenchymal to epithelial transition; IEA:Ensembl GO; GO:0007498; P:mesoderm development; TAS:ProtInc GO; GO:0048644; P:muscle organ morphogenesis; IEA:Ensembl GO; GO:0050884; P:neuromuscular process controlling posture; IEA:Ensembl GO; GO:0048339; P:paraxial mesoderm development; IEA:Ensembl GO; GO:0036342; P:post-anal tail morphogenesis; IEA:Ensembl GO; GO:1903053; P:regulation of extracellular matrix organization; IEA:Ensembl GO; GO:0006357; P:regulation of transcription by RNA polymerase II; TAS:ProtInc GO; GO:0003016; P:respiratory system process; IEA:Ensembl GO; GO:0048705; P:skeletal system morphogenesis; IEA:Ensembl GO; GO:0043588; P:skin development; IEA:Ensembl GO; GO:0001756; P:somitogenesis; IEA:Ensembl CDD; cd00083; HLH; 1 Gene3D;; -; 1 InterPro; IPR011598; bHLH_dom InterPro; IPR036638; HLH_DNA-bd_sf Pfam; PF00010; HLH; 1 SMART; SM00353; HLH; 1 SUPFAM; SSF47459; SSF47459; 1 PROSITE; PS50888; BHLH; 1 2: Evidence at transcript level; Complete proteome; Developmental protein; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation CHAIN 1 199 Transcription factor 15 /FTId=PRO_0000127460 DOMAIN 72 124 bHLH. {ECO:0000255|PROSITE- ProRule:PRU00981} COMPBIAS 52 66 Gly-rich CONFLICT 114 114 V -> L (in Ref. 1; AAA19969) CONFLICT 155 158 ADGG -> PTR (in Ref. 1; AAA19969) SEQUENCE 199 AA; 20816 MW; A3BF546A24ACF68A CRC64; MAFALLRPVG AHVLYPDVRL LSEDEENRSE SDASDQSFGC CEGPEAARRG PGPGGGRRAG GGGGAGPVVV VRQRQAANAR ERDRTQSVNT AFTALRTLIP TEPVDRKLSK IETVRLASSY IAHLANVLLL GDSADDGQPC FRAAGSAKGA VPAAADGGRQ PRSICTFCLS NQRKGGGRRD LGGSCLKVRG VAPLRGPRR
Research Areas
Citations (0)

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The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding.


Guo, P., et al. J. Biol. Chem. 284(27):18184-18193(2009)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
Hidai, H., et al. Genomics 30(3):598-601(1995)
Quertermous, E.E., et al. Proc. Natl. Acad. Sci. U.S.A. 91(15):7066-7070(1994)

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$ 325.00
$ 109.00
Cat# AP18248c
Availability: In Stock
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