|Application ||WB, E|
|Calculated MW||33196 Da|
|Antigen Region||29-56 aa|
|Other Names||Syntaxin-11, STX11|
|Target/Specificity||This STX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-56 amino acids from the N-terminal region of human STX11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STX11 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network.|
|Cellular Location||Membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis.
Marsh, R.A., et al. Pediatr Blood Cancer 55(1):134-140(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Danielian, S., et al. J. Clin. Immunol. 30(2):330-337(2010)
zur Stadt, U., et al. Am. J. Hum. Genet. 85(4):482-492(2009)
Marcelin, G., et al. Mamm. Genome 20(3):131-139(2009)
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